NADH (or Nicotinamide Adenine Dinucleotide + Hydrogen, or coenzyme 1) is the active coenzyme form of Vitamin B3 (niacin). Every cell in your body contains NADH. NADH is known for increased alertness, clarity, focus, memory, enhanced mood and energy, and is a potent antioxidant and free radical scavenger.
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NADH (or Nicotinamide Adenine Dinucleotide + Hydrogen, or coenzyme 1) is the active coenzyme form of Vitamin B3 (niacin). Every cell in your body contains NADH. NADH is known for increased alertness, clarity, focus, memory, enhanced mood and energy, and is a potent antioxidant and free radical scavenger How does NADH work in the brain? NADH boosts brain health in several ways. NADH increases the production ATP. NADH carries the electrons needed for the synthesis of ATP. Your brain cell mitochondria depend on this fuel (ATP) to function and stay healthy. By providing the means for ATP synthesis, NADH is involved in cognition, focus, concentration, memory, and processing speed. NADH plays an important role in mediating brain ageing and tissue damage, possibly decreasing the damage done by strokes. In one double-blind, placebo-controlled study researchers did a 3-month trial with Chronic Fatigue Syndrome patients. 86 patients were chosen to receive either 20mg of NADH daily or a placebo for the first 2-months. Mean age of the participants was 47 years. The study measured the intensity of fatigue, functional performance, mood state, functional impact of fatigue, quality of life, sleep quality and exercise capacity. Each was measured prior to the study and then at 30, 60 and 90 days. The study found that oral administration of NADH resulted in decreased anxiety and maximum heart rate. 2. NADH increases neurotransmitters. NADH is directly involved in the production of the critical neurotransmitters dopamine and also norepinephrine. Dopamine is involved in mood, energy, sexual drive, concentration, memory and muscle movement. Research has shown that people with low levels are far more vulnerable to addiction, disease and other chronic conditions. Energy Production.. The body, just like a car, needs fuel. Our primary source of fuel is fats, proteins, and carbohydrates in our diet. After digestion in the stomach, food- stuffs are absorbed into the blood and circulate to various tissues and cells where they are broken down into even smaller particles. One of these is a two-carbon molecule known as acetyl. Enzymes help break down these fats, proteins, and carbs into acetyl and they then help extract the final energy from acetyl. Enzymes also need helpers, and these helpers are called co-enzymes. Most of the co-enzymes are partly made from vitamins, such as vitamins E, C, lipoate, and riboflavin (B2). NADH, through a series of reactions with acetyl and oxygen, is able to produce energy. This energy is in the form of ATP (adenosine triphosphate). Therefore, a good supply optimizes energy production in the body. NADH even helps relieve symptoms related to jet lag and has been shown to alleviate the symptoms of Chronic Fatigue Syndrome including less brain fog, improved mood and energy, and better cognition.